Common use of Labedra 20
Labedra 20 (Vardenafil 20) is an oral drug used to treat erectile dysfunction. Sexual stimulation causes the production and release of nitric oxide from the nerve endings of the cavernous bodies of the penis hereby activating the enzyme guanylate cyclase. Guanylate cyclase in its turn is responsible for the production of cyclic guanosine monophosphate (cGMP). The cGMP causes widening and relaxation of the blood vessels carrying blood to the penis. Labedra 20 prevents phosphodiesterase-5 enzyme from destroying cGMP and thus helps to support blood flow to the penis.
Labedra 20 Dosage and direction
The recommended dose of Labedra 20 is 20 mg per day taken an hour before intercourse. If no side effects are experienced the dosage can be increased up to 20 mg. In case of adverse effects, the dose is reduced to 5 mg daily. Do not take more than one tab of Vardenafil 20 a day.
Labedra 20 Precautions
Labedra 20 has not been studied in people with cardiovascular disease, so it is preferable to avoid Labedra 20 in patients who have had a stroke heart failure, or a heart attack in history especially within the last six months. Before taking Vardenafil 20 inform your doctor if you have kidney or liver problems, a bleeding disorder, stomach ulcer, or an inherited retinal disorder such as retinitis pigmentosa, allergic reaction to this medicine or any other medicines, deformation of the penis such as angulation, cavernous fibrosis (Peyronie’s disease), as well as in diseases that contribute to the development of priapism (sickle-cell anemia, multiple myeloma, leukemia, or leukemia).
Contraindications
Labedra 20 is contraindicated in patients with hypersensitivity to its ingredients, ones treated with organic nitrates, in patients under 16 y.o., or those who take HIV protease inhibitors such as indinavir and ritonavir.
Labedra 20 side effect
Vardenafil 20 is usually well tolerated and side effects if occur are transient. The most frequent side effects are:
- Headache
- Flushing (hyperemia of the person)
- Frequent
- Dizziness
- Diarrhea phenomenon
- Nausea
- Nasal congestion
More rare and uncommon adverse effects are
- Photosensitivity of the skin
- Hypertension
- Back pain
- Watery eyes
- Hypotension
- Myalgia
- Priapism
Drug interaction
Labedra 20’s metabolism is inhibited by
- Erythromycin
- Ketoconazole (Nizoral)
- Itraconazole (Sporanox)
- Indinavir (Crixivan)
- Ritonavir (Ritomune)
Labedra 20 reduces the concentration of ritonavir and indinavir. In patients treated with nitrates, Labedra 20 may aggravate chest pain by increasing heart rate and lowering blood pressure. Vardenafil 20 is able to exaggerate the blood pressure-lowering effects of alpha-blocking drugs (terazosin or Hytrin). Vardenafil 20 never should be administered in patients who are treated with organic nitrates.
Missed dose
Labedra 20 is taken when needed but not more often than once daily so missed dose is not supposed.
Overdose
Symptoms of overdose include pain in the back, jaw, and arm, blindness, blurred vision, chest pain or discomfort, decreased vision, and blurred vision.
Storage
Store at room temperature between 15-30 C (59-86 F) away from children, pets, moisture and sunlight.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim the reliability of this information and the mistakes it could contain. We are not responsible for any direct, indirect, special, or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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